ITGB1 抗体
(7 references)Quick Overview for ITGB1 抗体 (ABIN967378)
抗原
See all ITGB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Mouse endothelial cell line
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亚型
- IgG2a kappa
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anti-Integrin beta 1 (ITGB1) (AA 25-100) antibody
ITGB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人, 猴 WB, FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人, Pig, 犬 WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-101A unconjugated
anti-Integrin beta 1 (ITGB1) antibody (PE)ITGB1 适用: 人, Pig, 犬 FACS 宿主: 小鼠 Monoclonal MEM-101A PE
anti-Integrin beta 1 (ITGB1) (AA 297-380) antibodyITGB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) antibodyITGB1 适用: 人 WB, FACS, ELISA, IHC, IF 宿主: 兔 Monoclonal 32A10 unconjugated Recombinant Antibody
anti-Integrin beta 1 (ITGB1) (AA 454-714) antibodyITGB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 1 (ITGB1) (AA 140-383) antibodyITGB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Integrin beta 1 (ITGB1) (Subunit 1 beta) antibody (FITC)ITGB1 适用: 人 FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal FITC
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应用备注
- For IHC, we recommend the use of purified 9EG7 mAb in our special formulation for immunohistochemistry.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4° C.
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: "A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules." in: European journal of immunology, Vol. 28, Issue 3, pp. 926-35, (1998) (PubMed).
: "Adhesion of lymphoma cells to fibronectin: differential use of alpha 4 beta 1 and alpha 5 beta 1 integrins and stimulation by the 9EG7 mAb against the murine beta 1 integrin subunit." in: Cell adhesion and communication, Vol. 3, Issue 4, pp. 327-36, (1996) (PubMed).
: "A role in migration for the alpha V beta 1 integrin expressed on oligodendrocyte precursors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 22, pp. 7240-52, (1996) (PubMed).
: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).
: "Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion." in: The Journal of biological chemistry, Vol. 269, Issue 31, pp. 19859-67, (1994) (PubMed).
: "The integrin chains beta 1 and alpha 6 associate with the chaperone calnexin prior to integrin assembly." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12263-8, (1994) (PubMed).
: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).
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: "A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules." in: European journal of immunology, Vol. 28, Issue 3, pp. 926-35, (1998) (PubMed).
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- ITGB1 (Integrin beta 1 (ITGB1))
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别名
- CD29
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背景
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The 9EG7 antibody reacts with the 130-kDa integrin beta1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin alpha chains. With alpha1 through alpha6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with alphav (CD51), it forms alphavbeta1 integrin. It also associates with the integrin alpha7 alpha8 and alpha9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. 9EG7 mAb has been shown to inhibit both the alpha6beta1-mediated binding of lymphocytes to endothelial cells and the adhesion mediated by activated, but not unactivated, alpha4beta1-integrin. The source of the immunogen was mouse lymph node-derived endothelial cell line TME.
Synonyms: Integrin beta1 chain -
途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
抗原
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