ZAP70 抗体
Quick Overview for ZAP70 抗体 (ABIN967272)
抗原
See all ZAP70 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Zap-70 (Ab-493) antibody detects endogenous levels of total Zap-70 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human Zap-70 around the phosphorylation site of tyrosine 493 (S-Y-YP-T-A).
-
-
-
-
应用备注
- IHC: 1:50-1:100.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 100ug/100ul.
-
缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
-
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).
: "Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function." in: Molecular and cellular biology, Vol. 16, Issue 9, pp. 5026-35, (1996) (PubMed).
: "Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function." in: The EMBO journal, Vol. 14, Issue 11, pp. 2499-508, (1995) (PubMed).
: "
-
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).
-
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
-
别名
- Zap-70
-
途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
-