UBA7 抗体
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北京 101111
Quick Overview for UBA7 抗体 (ABIN967228)
抗原
See all UBA7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human UBE1L expressed in E. Coli.
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亚型
- IgG1
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anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 429-488) antibody
UBA7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 1-1012) antibodyUBA7 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (C-Term) antibodyUBA7 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 1-1012) antibodyUBA7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (C-Term) antibodyUBA7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 1-1012) antibodyUBA7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) antibodyUBA7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2660 unconjugated Recombinant Antibody
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (N-Term) antibodyUBA7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) antibodyUBA7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1770 unconjugated Recombinant Antibody
anti-Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) antibodyUBA7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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: "UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 3806-11, (2002) (PubMed).
: "A gene from human chromosome region 3p21 with reduced expression in small cell lung cancer." in: Cancer research, Vol. 52, Issue 6, pp. 1536-41, (1992) (PubMed).
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- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
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别名
- UBE1L
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting.
Tissue specificity: Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferonstimulated gene 15 protein.
Synonyms: D8, UBE2, UBA1B, UBE1L, MGC12713, UBA7 -
分子量
- 112kDa
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基因ID
- 7318
抗原
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