ASPSCR1 抗体
Quick Overview for ASPSCR1 抗体 (ABIN967214)
抗原
See all ASPSCR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Antibodies are purified by protein A affinity chromatography
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亚型
- IgG1
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应用备注
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Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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缓冲液
- PBS with 0.2%BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).
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: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).
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- ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
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别名
- TUG
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背景
- The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
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基因ID
- 68938
抗原
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