TIMP3 抗体 (N-Term)
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北京 101111
Quick Overview for TIMP3 抗体 (N-Term) (ABIN967183)
抗原
See all TIMP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of African clawed frog TIMP3(Metalloproteinase inhibitor 3 precursor)
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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别名
- TIMP3
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背景
- TIMP3(Metalloproteinase inhibitor 3) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. TIMP3 may form part of a tissue-specific acute response to remodeling stimuli. TIMP3 is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. Defects in TIMP3 are the cause of Sorsby's fundus dystrophy (SFD). SFD is a rare autosomal dominant macular disorder with an age of onset in the fourth decade. It is characterized by loss of central vision from subretinal neovascularization and atrophy of the occular tissues.
抗原
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