SOCS2 抗体 (C-Term)
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北京 101111
Quick Overview for SOCS2 抗体 (C-Term) (ABIN967065)
抗原
See all SOCS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-198, C-Term
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS2 (181-198 aa), identical to the related mouse and rat sequence.
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anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibody
SOCS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodyKO Validated SOCS2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3570 unconjugated Recombinant Antibody
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 99-198) antibodySOCS2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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溶解方式
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
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缓冲液
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
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储存液
- Thimerosal (Merthiolate), Sodium azide
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储存条件
- -20 °C
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: "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 6, pp. 1394-406, (2002) (PubMed).
: "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24095-101, (1998) (PubMed).
: "Cloning and characterization of novel CIS family genes." in: Biochemical and biophysical research communications, Vol. 239, Issue 2, pp. 439-46, (1997) (PubMed).
: "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3." in: Biochemical and biophysical research communications, Vol. 237, Issue 1, pp. 79-83, (1997) (PubMed).
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: "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 6, pp. 1394-406, (2002) (PubMed).
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- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
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别名
- SOCS2
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背景
- Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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