SMAD1 抗体 (C-Term)
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北京 101111
Quick Overview for SMAD1 抗体 (C-Term) (ABIN967044)
抗原
See all SMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 1 (SMAD1) detection. Tested with WB in Human, Mouse, Rat.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human Smad 1,2,3,5, identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-240) antibody
SMAD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2A1 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 202-335) antibodySMAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer187) antibodySMAD1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-330) antibodySMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1356CT119-18-55 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB43846 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer465) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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: "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation." in: Nature, Vol. 400, Issue 6745, pp. 687-93, (1999) (PubMed).
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: "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation." in: Nature, Vol. 400, Issue 6745, pp. 687-93, (1999) (PubMed).
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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别名
- Mothers against decapentaplegic homolog 1(MAD homolog 1/Mothers against DPP homolog 1)
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背景
- SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-beta superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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