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SIRT6 抗体 (C-Term)

SIRT6 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN967032
发货至: 中国
  • 抗原 See all SIRT6 抗体
    SIRT6 (Sirtuin 6 (SIRT6))
    抗原表位
    • 16
    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 92
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 88
    • 12
    • 2
    克隆类型
    • 83
    • 19
    多克隆
    标记
    • 53
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT6 antibody is un-conjugated
    应用范围
    • 83
    • 40
    • 36
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6)
    Top Product
    Discover our top product SIRT6 Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C
  • Kawahara, Michishita, Adler, Damian, Berber, Lin, McCord, Ongaigui, Boxer, Chang, Chua: "SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span." in: Cell, Vol. 136, Issue 1, pp. 62-74, (2009) (PubMed).

    Michishita, McCord, Berber, Kioi, Padilla-Nash, Damian, Cheung, Kusumoto, Kawahara, Barrett, Chang, Bohr, Ried, Gozani, Chua: "SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin." in: Nature, Vol. 452, Issue 7186, pp. 492-6, (2008) (PubMed).

    Kanfi, Shalman, Peshti, Pilosof, Gozlan, Pearson, Lerrer, Moazed, Marine, de Cabo, Cohen: "Regulation of SIRT6 protein levels by nutrient availability." in: FEBS letters, Vol. 582, Issue 5, pp. 543-8, (2008) (PubMed).

  • 抗原
    SIRT6 (Sirtuin 6 (SIRT6))
    别名
    SIRT6 (SIRT6 产品)
    别名
    2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
    背景
    SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6) is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT6 (Mono-ADPribosyltransferase sirtuin-6) is included in class IV of the sirtuin family. SIRT6 (Mono-ADPribosyltransferase sirtuin-6) contains 1 deacetylase sirtuin-type domain.
    Synonyms: SIR2L6(SIR2-like protein 6)
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