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SCD 抗体

SCD 适用: 人, 小鼠 WB, ELISA, IHC, IP Monoclonal unconjugated
产品编号 ABIN966997
发货至: 中国
  • 抗原 See all SCD 抗体
    SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
    适用
    • 40
    • 21
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    请咨询
    克隆类型
    • 37
    • 4
    单克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCD antibody is un-conjugated
    应用范围
    • 28
    • 14
    • 13
    • 13
    • 9
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    特异性
    Full length recombinant protein. Reacts with human and mouse proteins.
    亚型
    IgG2b
    Top Product
    Discover our top product SCD Primary Antibody
  • 应用备注
    Western blot, ELISA, IP, and IHC in obesity research.
    限制
    仅限研究用
  • 浓度
    1mg/ml
    缓冲液
    PBS, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
    别名
    SCD1 (SCD 产品)
    背景
    Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.
    基因ID
    20249
    途径
    Brown Fat Cell Differentiation
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