Mu Opioid Receptor 1 抗体 (C-Term)
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Quick Overview for Mu Opioid Receptor 1 抗体 (C-Term) (ABIN966719)
抗原
See all Mu Opioid Receptor 1 (OPRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very Cterminal residues of human OPRM1(Mu-type opioid receptor)
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anti-Opioid Receptor, mu 1 (OPRM1) (C-Term) antibody
OPRM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (AA 22-38), (Extracellular), (N-Term) antibodyOPRM1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, LCI, ICC 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (pSer375) antibodyOPRM1 适用: 小鼠 WB, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (AA 165-270) antibodyOPRM1 适用: 小鼠, 大鼠 WB, IHC (p), IF (p), ICC, IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (C-Term) antibodyOPRM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (AA 1-68) antibodyOPRM1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (AA 161-187) antibodyOPRM1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22405 unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (pSer375) antibodyOPRM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (AA 1-110) antibodyOPRM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Opioid Receptor, mu 1 (OPRM1) (C-Term) antibodyOPRM1 适用: 人, 猴, Cow, Pig, 犬, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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储存条件
- 4 °C
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: "Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene." in: Journal of neurochemistry, Vol. 108, Issue 4, pp. 962-72, (2009) (PubMed).
: "Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm." in: Neuroscience, Vol. 133, Issue 1, pp. 209-20, (2005) (PubMed).
: "Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X." in: Biochemical and biophysical research communications, Vol. 301, Issue 4, pp. 1057-61, (2003) (PubMed).
: "The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 14, pp. 7752-5, (1999) (PubMed).
: "The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 15, Issue 3 Pt 2, pp. 2396-406, (1995) (PubMed).
: "Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment." in: FEBS letters, Vol. 338, Issue 2, pp. 217-22, (1994) (PubMed).
: "Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain." in: FEBS letters, Vol. 354, Issue 2, pp. 213-6, (1994) (PubMed).
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: "Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene." in: Journal of neurochemistry, Vol. 108, Issue 4, pp. 962-72, (2009) (PubMed).
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- Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))
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别名
- OPRM1
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背景
- OPRM1(Mu-type opioid receptor) inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. OPRM1forms a complex with G(alpha)z/i2 subunits and the RGSZ proteins, RGSZ17 and RGSZ20. The formation of this complex results in mu-opioid receptor desensitization. OPRM1 interacts with RGSZ17 and RGSZ20. OPRM1 is a multi-pass membrane protein. The polymorphism Variant Asp-40 does not show altered binding affinities for most opioid peptides and alkaloids tested, but it binds beta-endorphin, an endogenous opioid that activates the mu opioid receptor, approximately 3 times more tightly than the most common allelic form. OPRM1(Mu-type opioid receptor) belongs to the G-protein coupled receptor 1 family.
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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