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Merlin 抗体

Cited in 3+ publications. This anti-Merlin antibody is a 兔 多克隆 antibody detecting Merlin in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN966568
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Merlin 抗体 (ABIN966568)

抗原

See all Merlin (NF2) 抗体
Merlin (NF2) (Neurofibromin 2 (NF2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 87
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多克隆

标记

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This Merlin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 特异性

    Merlin (Ab-518) antibody detects endogenous levels of total Merlin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
  • 应用备注

    WB: 1:500~1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Xiao, Gallagher, Shetler, Skele, Altomare, Pestell, Jhanwar, Testa: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, (2005) (PubMed).

    Ratner, Bryan, Weber, Nguyen, Barnes, Pitt, Gelber, Cheung, Prince: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, (2001) (PubMed).

    Böhni, Hemmi, Aguet: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, (1994) (PubMed).

  • 抗原

    Merlin (NF2) (Neurofibromin 2 (NF2))

    别名

    Merlin

    途径

    Cell-Cell Junction Organization
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