Merlin 抗体
Quick Overview for Merlin 抗体 (ABIN966568)
抗原
See all Merlin (NF2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Merlin (Ab-518) antibody detects endogenous levels of total Merlin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
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应用备注
- WB: 1:500~1:1000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, (2005) (PubMed).
: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, (2001) (PubMed).
: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, (1994) (PubMed).
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: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, (2005) (PubMed).
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- Merlin (NF2) (Neurofibromin 2 (NF2))
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别名
- Merlin
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途径
- Cell-Cell Junction Organization
抗原
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