Influenza A Matrix Protein 2 抗体 (Influenza A Virus) (N-Term)
M2
适用: Influenza A Virus
IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Influenza A Matrix Protein 2 (M2) 抗体
- Influenza A Matrix Protein 2 (M2)
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抗原表位
- N-Term
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适用
- Influenza A Virus
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Purified by antigen-specific affinity chromatography.
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of influenza A virus Matrix protein M2
- Top Product
- Discover our top product M2 Primary Antibody
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- 应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- This antibody is stored in PBS, 50% glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- Influenza A Matrix Protein 2 (M2)
- Abstract
- M2 产品
- 物质类
- Influenza Protein
- 背景
- The Matrix protein M2 forms a protons channel. When the environmental pH is lower than a threshold, the M2 channel is activated and selectively transports protons accross the membrane from the extracellular side to the cytoplasmic side. It is crucial for the uncoating process. When the virion is internalized into the endosome the channel can acidify the virion interior, promoting the dissociation of the viral matrix protein (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell's nucleus. For some influenza virus subtypes, the M2 channel can elevate the intravesicular pH of the trans-Golgi network, preventing the viral protein haemagglutinin, which is transported to the cell surface through the trans-Golgi network, from incorrect maturation in an otherwise low pH environment
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