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L3MBTL1 抗体 (N-Term)

Name: L3MBTL1 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN966472
Availability: OutOfStock

This anti-L3MBTL1 antibody is a 兔多克隆 antibody detecting L3MBTL1 in IHC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

(3 references)

产品编号 ABIN966472

发货至: 中国

Quick Overview for L3MBTL1 抗体 (N-Term) (ABIN966472)

抗原

See all L3MBTL1 抗体

L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This L3MBTL1 antibody is un-conjugated

应用范围

Immunohistochemistry (IHC)

Discover our top product L3MBTL1 Primary Antibody

抗原表位
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N-Term

免疫原

Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human L3MBTL(Lethal(3)malignant brain tumor-like protein )
anti-L(3)mbt-Like 1 (L3MBTL1) (Center) antibody
L3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 1-772) antibody
L3MBTL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 82-298) antibody
L3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 513-752) antibody
L3MBTL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 451-485) antibody
L3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 221-270) antibody
L3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 442-491) antibody
L3MBTL1 适用: 人, 小鼠, 犬, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (N-Term) antibody
L3MBTL1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (AA 144-193) antibody
L3MBTL1 适用: 人, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated

anti-L(3)mbt-Like 1 (L3MBTL1) (C-Term) antibody
L3MBTL1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated

限制

仅限研究用
储存条件

4 °C
Boccuni, MacGrogan, Scandura, Nimer: "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 15412-20, (2003) (PubMed).

Wang, Tereshko, Boccuni, MacGrogan, Nimer, Patel: "Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets." in: Structure (London, England : 1993), Vol. 11, Issue 7, pp. 775-89, (2003) (PubMed).

Koga, Matsui, Hirota, Takebayashi, Okumura, Saya: "A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes." in: Oncogene, Vol. 18, Issue 26, pp. 3799-809, (1999) (PubMed).
抗原

L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

别名

L3MBTL

背景

L3MBTL(Lethal(3)malignant brain tumor-like protein ) is polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL participates in the ETV6-mediated repression. L3MBTL probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis. L3MBTL interacts with ETV6 and is widely expressed. Expression is reduced in colorectal cancer cell line SW480 and promyelocytic leukemia cell line HL-60. In interphase cells, it is scattered throughout the nucleoplasm. In mitotic cells, it strongly associates with condensed chromosomes from the prophase to telophase.
Synonyms: KIAA0681, L3MBT, L3MBTL1

途径

Chromatin Binding