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Inhibin alpha 抗体

INHA 适用: 人 WB, IHC, ELISA Monoclonal unconjugated
产品编号 ABIN966402
发货至: 中国
  • 抗原 See all Inhibin alpha (INHA) 抗体
    Inhibin alpha (INHA) (Inhibin, alpha (INHA))
    适用
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    克隆类型
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    单克隆
    标记
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    This Inhibin alpha antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    Ni-NTA purified truncated recombinant INHA expressed in E. Coli strain BL21 (DE3)
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product INHA Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 1,000
    IHC(P): 1: 1,000- 1: 2,000
    ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 储存条件
    -20 °C
  • Knight: "Roles of inhibins, activins, and follistatin in the female reproductive system." in: Frontiers in neuroendocrinology, Vol. 17, Issue 4, pp. 476-509, (1997) (PubMed).

    Fahy, Wilson, Beard, Groome, Knight et al.: "Changes in inhibin-A (alpha-beta A dimer) and total alpha inhibin in the peripheral circulation and ovaries of rats after gonadotrophin-induced follicular development and during the normal oestrous ..." in: The Journal of endocrinology, Vol. 147, Issue 2, pp. 271-83, (1996) (PubMed).

    Lambert-Messerlian, Crowley, Schneyer: "Extragonadal alpha-inhibin precursor proteins circulate in human male serum." in: The Journal of clinical endocrinology and metabolism, Vol. 80, Issue 10, pp. 3043-9, (1995) (PubMed).

    Mayo, Cerelli, Spiess, Rivier, Rosenfeld, Evans, Vale: "Inhibin A-subunit cDNAs from porcine ovary and human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 16, pp. 5849-53, (1986) (PubMed).

  • 抗原
    Inhibin alpha (INHA) (Inhibin, alpha (INHA))
    别名
    INHA (INHA 产品)
    别名
    si:dkey-91f15.2 antibody, INHA antibody, MGC108500 antibody, AW555078 antibody, inhibin, alpha antibody, inhibin alpha subunit antibody, inhibin alpha antibody, inhibin alpha L homeolog antibody, inha antibody, INHA antibody, inha.L antibody, Inha antibody
    背景
    INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
    基因ID
    3623
    途径
    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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