HTR2A 抗体 (C-Term)
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Quick Overview for HTR2A 抗体 (C-Term) (ABIN966325)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 418-432, C-Term
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human HTR2A (418-432 aa), different from the mouse sequence by one amino acid.
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限制
- 仅限研究用
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缓冲液
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
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储存液
- Thimerosal (Merthiolate), Sodium azide
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储存条件
- -20 °C
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: "The human polyomavirus, JCV, uses serotonin receptors to infect cells." in: Science (New York, N.Y.), Vol. 306, Issue 5700, pp. 1380-3, (2004) (PubMed).
: "Primary structure of the human platelet serotonin 5-HT2A receptor: identify with frontal cortex serotonin 5-HT2A receptor." in: Journal of neurochemistry, Vol. 63, Issue 2, pp. 465-9, (1994) (PubMed).
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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别名
- HTR2A
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背景
- The mammalian HTR2A 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones.5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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