Purified by antigen-specific affinity chromatography.
免疫原
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle residues of human GDC(Grave's disease carrier protein)
GDC(Grave's disease carrier protein) is required for the accumulation of coenzyme A in the mitochondrial matrix. GDC is an integral membrane protein and is localized in mitochondrial inner membrane. The protein has a possible role in Graves' disease. GDC is recognized by IgG from patients with active Grave's disease. GDC belongs to the mitochondrial carrier family. SLC25A16 contains 3 Solcar repeats.