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Dynamin 1 抗体

Cited in 1 publication. This not_set 单克隆 anti-Dynamin 1 antibody specifically detects Dynamin 1 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN966017
发货至: 中国
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Quick Overview for Dynamin 1 抗体 (ABIN966017)

抗原

See all Dynamin 1 (DNM1) 抗体
Dynamin 1 (DNM1)

适用

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克隆类型

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单克隆

标记

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This Dynamin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 特异性

    Ni-NTA purified truncated recombinant Dynamin-1 expressed in E. Coli strain BL21 (DE3)

    纯化方法

    Crude ascites.

    亚型

    IgG2a
  • 应用备注

    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C
  • Yoo, Jeong, Kwon, Hur, Park, Han: "Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 11904-9, (2002) (PubMed).

  • 抗原

    Dynamin 1 (DNM1)

    别名

    Dynamin-1

    背景

    Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

    途径

    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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