Dynamin 1 抗体
Quick Overview for Dynamin 1 抗体 (ABIN966017)
抗原
See all Dynamin 1 (DNM1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant Dynamin-1 expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Crude ascites.
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亚型
- IgG2a
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应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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: "Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 11904-9, (2002) (PubMed).
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: "Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 11904-9, (2002) (PubMed).
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- Dynamin 1 (DNM1)
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别名
- Dynamin-1
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背景
- Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
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途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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