KRT8 抗体 (AA 391-483)
Quick Overview for KRT8 抗体 (AA 391-483) (ABIN965965)
抗原
See all KRT8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 391-483
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).
: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
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: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).
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- KRT8 (Keratin 8 (KRT8))
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别名
- Cytokeratin 8
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背景
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Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms: CK8, CYK8, K2C8, KRT8 -
分子量
- 54kDa
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基因ID
- 3856
抗原
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