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KRT8 抗体 (AA 391-483)

This 小鼠 单克隆 antibody specifically detects KRT8 in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN965965
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KRT8 抗体 (AA 391-483) (ABIN965965)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

克隆位点

8A5D12
  • 抗原表位

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    AA 391-483

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Wang, He, Tsao, Cheung, Wong, Chiu: "Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization." in: Cancer letters, Vol. 265, Issue 2, pp. 188-96, (2008) (PubMed).

    Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).

  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    Cytokeratin 8

    背景

    Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
    Synonyms: CK8, CYK8, K2C8, KRT8

    分子量

    54kDa

    基因ID

    3856
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