Cytokeratin 19 抗体 (C-Term)
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北京 101111
Quick Overview for Cytokeratin 19 抗体 (C-Term) (ABIN965901)
抗原
See all Cytokeratin 19 (KRT19) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for Keratin, type I cytoskeletal 19 (KRT19) detection. Tested with WB, IHC-P, ICC in Human.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human CK19.< br/>Immunogen was affinity purified.
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).
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: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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别名
- Keratin, type I cytoskeletal 19
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背景
- Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene. The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
抗原
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