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ChT 抗体 (C-Term)

This anti-ChT antibody (ABIN965895) is a Rabbit Polyclonal antibody detecting ChT in IHC. Suitable for Mouse, Human, Rat.
产品编号 ABIN965895
发货至: 中国

Quick Overview for ChT 抗体 (C-Term) (ABIN965895)

抗原

See all ChT 抗体
ChT (High Affinity Choline Transporter (ChT))

适用

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小鼠, 人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ChT antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human choline transporter
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Apparsundaram, Ferguson, George, Blakely: "Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." in: Biochemical and biophysical research communications, Vol. 276, Issue 3, pp. 862-7, (2000) (PubMed).

  • 抗原

    ChT (High Affinity Choline Transporter (ChT))

    别名

    CHT1

    背景

    The choline transporter is a hemicholinium-3-sensitive phosphorylated transmembrane protein, the protein regulates high-affinity choline uptake, and plays the roles in disease states. CHT1(High-affinity choline transporter 1) imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. CHT1 is sodium ionand chloride ion-dependent. CHT1 is expressed in putamen, spinal cord and medulla and is specific for cholinergic neurons. CHT1 is specifically inhibited by nanomolar concentrations of hemicholinium 3. CHT1 belongs to the sodium: solute symporter (SSF) (TC 2.A.21) family.
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