ChT 抗体 (C-Term)
Quick Overview for ChT 抗体 (C-Term) (ABIN965895)
抗原
See all ChT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human choline transporter
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." in: Biochemical and biophysical research communications, Vol. 276, Issue 3, pp. 862-7, (2000) (PubMed).
: "
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Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." in: Biochemical and biophysical research communications, Vol. 276, Issue 3, pp. 862-7, (2000) (PubMed).
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- ChT (High Affinity Choline Transporter (ChT))
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别名
- CHT1
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背景
- The choline transporter is a hemicholinium-3-sensitive phosphorylated transmembrane protein, the protein regulates high-affinity choline uptake, and plays the roles in disease states. CHT1(High-affinity choline transporter 1) imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. CHT1 is sodium ionand chloride ion-dependent. CHT1 is expressed in putamen, spinal cord and medulla and is specific for cholinergic neurons. CHT1 is specifically inhibited by nanomolar concentrations of hemicholinium 3. CHT1 belongs to the sodium: solute symporter (SSF) (TC 2.A.21) family.
抗原
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