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- 抗原 See all CHD3 抗体
- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CHD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CHD3 expressed in E. Coli.
- 克隆位点
- 2G4
- 亚型
- IgG1
- Top Product
- Discover our top product CHD3 Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).
: "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. ..." in: Molecular cell, Vol. 15, Issue 6, pp. 853-65, (2004) (PubMed).
: "Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function." in: Biochemistry, Vol. 42, Issue 30, pp. 9091-101, (2003) (PubMed).
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UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).
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- 抗原
- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
- 别名
- CHD3 (CHD3 产品)
- 背景
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This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Synonyms: ZFH, Mi-2a, Mi2ALPHA, CHD3 - 分子量
- 226kDa
- 基因ID
- 1107
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