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CDK1 抗体

This anti-CDK1 antibody is a 小鼠 单克隆 antibody detecting CDK1 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 猴. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN965841
发货至: 中国

Quick Overview for CDK1 抗体 (ABIN965841)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 253
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小鼠

克隆类型

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单克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

2G9
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CDK1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • McMullin: "The classification and diagnosis of erythrocytosis." in: International journal of laboratory hematology, Vol. 30, Issue 6, pp. 447-59, (2008) (PubMed).

    Marash, Liberman, Henis-Korenblit, Sivan, Reem, Elroy-Stein, Kimchi: "DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis." in: Molecular cell, Vol. 30, Issue 4, pp. 447-59, (2008) (PubMed).

  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
    Synonyms: CDC2, CDC28A, P34CDC2, MGC111195, DKFZp686L20222, CDK1

    分子量

    34kDa

    基因ID

    983

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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