Purified by antigen-specific affinity chromatography.
免疫原
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CDCA5 (Cell division cycle associated 5)
CDCA5
适用: 人, 小鼠
WB, FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 488
应用备注
ELISA, Western blotting: 1µg/ml for 2hrs.
限制
仅限研究用
状态
Liquid
缓冲液
This antibody is stored in PBS, 50% glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
抗原
CDCA5
(Cell Division Cycle Associated 5 (CDCA5))
别名
CDCA5
背景
CDCA5(Cell division cycle associated 5) is a regulator of sister chromatid cohesion in mitosis. CDCA5 may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex. CDCA5 is found in a complex with cohesin components SMC1L1, SMC3L1 and RAD21, PDS5A/APRIN and PDS5B/SCC-112. The interaction with cohesin subunits is probably indirect, and is weak. CDCA5 was named Sororin after the Latin word soror, which means sister, because of its critical role in sister chromatid cohesion.