CDCA5 抗体 (N-Term)
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Quick Overview for CDCA5 抗体 (N-Term) (ABIN965837)
抗原
See all CDCA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CDCA5 (Cell division cycle associated 5)
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CDCA5 (Cell Division Cycle Associated 5 (CDCA5))
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别名
- CDCA5
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背景
- CDCA5(Cell division cycle associated 5) is a regulator of sister chromatid cohesion in mitosis. CDCA5 may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex. CDCA5 is found in a complex with cohesin components SMC1L1, SMC3L1 and RAD21, PDS5A/APRIN and PDS5B/SCC-112. The interaction with cohesin subunits is probably indirect, and is weak. CDCA5 was named Sororin after the Latin word soror, which means sister, because of its critical role in sister chromatid cohesion.
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途径
- Chromatin Binding
抗原
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