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CD19 抗体

This 单克隆 antibody specifically detects CD19 in WB, IHC 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN965770
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD19 抗体 (ABIN965770)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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宿主

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克隆类型

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单克隆

标记

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This CD19 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 特异性

    Ni-NTA purified recombinant human CD19 expressed in E. Coli strain M15.

    纯化方法

    Antibodies are purified by protein A affinity chromatography

    亚型

    IgG2a
  • 应用备注

    Western Blot: Dilution 1: 2000- 5,000
    IHC(P): Dilution 1: 100- 1: 400
    IHC(F): Dilution 1: 200- 1: 400
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • de Rie, Zeijlemaker, von dem Borne: "Inhibition, by vinca alkaloids and colchicine, of antigenic modulation induced by anti-CD19 monoclonal antibodies." in: Leukemia research, Vol. 12, Issue 2, pp. 135-41, (1988) (PubMed).

    De Rie, Zeijlemaker, Von dem Borne, Out: "Evaluation of a method of production and purification of monoclonal antibodies for clinical applications." in: Journal of immunological methods, Vol. 102, Issue 2, pp. 187-93, (1987) (PubMed).

  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    The CD19 antigen (95kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.

    基因ID

    930

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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