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Endoglin 抗体

ENG 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated
产品编号 ABIN965762
发货至: 中国
  • 抗原 See all Endoglin (ENG) 抗体
    Endoglin (ENG)
    适用
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    小鼠
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    标记
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    This Endoglin antibody is un-conjugated
    应用范围
    • 136
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CD105 expressed in E. Coli.
    克隆位点
    3A9
    亚型
    IgG1
    Top Product
    Discover our top product ENG Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Fujita, Ewing, Chan, Mangold, Partin, Isaacs, Pavlovich: "Endoglin (CD105) as a urinary and serum marker of prostate cancer." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).

    Sun: "Pharmacophore-based virtual screening." in: Current medicinal chemistry, Vol. 15, Issue 10, pp. 1018-24, (2008) (PubMed).

  • 抗原
    Endoglin (ENG)
    别名
    CD105 (ENG 产品)
    背景
    This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
    Synonyms: ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744
    分子量
    71kDa
    基因ID
    2022
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