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Endoglin 抗体

This anti-Endoglin antibody is a 小鼠 单克隆 antibody detecting Endoglin in WB, FACS, IHC, ELISA 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN965762
发货至: 中国

Quick Overview for Endoglin 抗体 (ABIN965762)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

3A9
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CD105 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Fujita, Ewing, Chan, Mangold, Partin, Isaacs, Pavlovich: "Endoglin (CD105) as a urinary and serum marker of prostate cancer." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).

    Sun: "Pharmacophore-based virtual screening." in: Current medicinal chemistry, Vol. 15, Issue 10, pp. 1018-24, (2008) (PubMed).

  • 抗原

    Endoglin (ENG)

    别名

    CD105

    背景

    This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
    Synonyms: ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744

    分子量

    71kDa

    基因ID

    2022
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