Capsid Protein Vp1 (Middle Region) 抗体
Cited in 8+ publications.
The 兔 多克隆 anti-Capsid Protein Vp1 antibody (ABIN965745) specifically detects Capsid Protein Vp1 in IHC.
The antibody is reactive with Norovirus samples.
(8 references)
产品编号 ABIN965745
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Capsid Protein Vp1 (Middle Region) 抗体 (ABIN965745)
抗原
Capsid Protein Vp1
适用
Norovirus
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC)
-
-
抗原表位
- Middle Region
-
免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of Norovirus Capsid protein VP1
-
-
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C
-
-
-
: "C-terminal arginine cluster is essential for receptor binding of norovirus capsid protein." in: Journal of virology, Vol. 80, Issue 15, pp. 7322-31, (2006) (PubMed).
: "The 3' end of Norwalk virus mRNA contains determinants that regulate the expression and stability of the viral capsid protein VP1: a novel function for the VP2 protein." in: Journal of virology, Vol. 77, Issue 21, pp. 11603-15, (2003) (PubMed).
: "Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns." in: The Journal of infectious diseases, Vol. 188, Issue 1, pp. 19-31, (2003) (PubMed).
: "X-ray crystallographic structure of the Norwalk virus capsid." in: Science (New York, N.Y.), Vol. 286, Issue 5438, pp. 287-90, (1999) (PubMed).
: "Biochemical characterization of a smaller form of recombinant Norwalk virus capsids assembled in insect cells." in: Journal of virology, Vol. 71, Issue 10, pp. 8066-72, (1997) (PubMed).
: "Attachment and entry of recombinant Norwalk virus capsids to cultured human and animal cell lines." in: Journal of virology, Vol. 70, Issue 10, pp. 6589-97, (1996) (PubMed).
: "Specific proteolytic cleavage of recombinant Norwalk virus capsid protein." in: Journal of virology, Vol. 69, Issue 3, pp. 1693-8, (1995) (PubMed).
: "Sequence and genomic organization of Norwalk virus." in: Virology, Vol. 195, Issue 1, pp. 51-61, (1993) (PubMed).
-
: "C-terminal arginine cluster is essential for receptor binding of norovirus capsid protein." in: Journal of virology, Vol. 80, Issue 15, pp. 7322-31, (2006) (PubMed).
-
- Capsid Protein Vp1
-
物质类
- Viral Protein
-
背景
-
Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. CP(Capsid protein VP1) attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells. Soluble capsid protein may play a role in viral immunoevasion. CP(Capsid protein VP1) binds to histo-blood group antigens at surface of target cells. The shell domain (S domain) contains elements essential for the formation of the icosahedron. The Protruding domain (P domain) is divided into sub-domains P1 and P2. P domain interacts in dimeric contacts that increase the stability of the capsid and form the protrusions on the virion. An hypervariable region in P2 is thought to play an important role in receptor binding and immune reactivity.
Synonyms: p59, Soluble capsid protein, p30 (Protein 30k)
抗原
-
You are here:
