Calpain 3 抗体 (C-Term)
Quick Overview for Calpain 3 抗体 (C-Term) (ABIN965743)
抗原
See all Calpain 3 (CAPN3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Purified by antigen-specific affinity chromatography.
-
免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CAPN3(Calpain-3)
-
-
anti-Calpain 3 (CAPN3) (AA 602-821) antibody
CAPN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 210-309) antibodyCAPN3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-Calpain 3 (CAPN3) (AA 603-632), (C-Term) antibodyCAPN3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18391 unconjugated
anti-Calpain 3 (CAPN3) (AA 582-821) antibodyCAPN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 582-821) antibodyCAPN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) antibodyCAPN3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) antibodyCAPN3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (AA 1-150) antibodyCAPN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 3 (CAPN3) (C-Term) antibodyCAPN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- This antibody is stored in PBS, 50% glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- Calpain 3 (CAPN3)
-
别名
- CAPN3
-
背景
- CAPN3(Calpain-3) is a calcium-regulated non-lysosomal thiol-protease. It has a broad endopeptidase specificity. CAPN3 is activated by micromolar concentrations of calcium and inhibited by calpastatin. It interacts with TTN/titin. Isoform I is skeletal muscle specific. Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A). LGMD2A is both autosomal dominantly and recessively transmitted. It is characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. CAPN3 belongs to the peptidase C2 family and contains 1 calpain catalytic domain and 4 EF-hand domains.
-
途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-
