CAPN1 抗体 (AA 312-326)
(1 reference)Quick Overview for CAPN1 抗体 (AA 312-326) (ABIN965738)
抗原
See all CAPN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 312-326
-
免疫原
- A synthetic peptide corresponding to a sequence at the middle region of human Calpain-1 (312-326 aa), different from the mouse sequence by two amino acids.
-
-
anti-Calpain 1 (CAPN1) (AA 625-713) antibody
CAPN1 适用: 人, 小鼠, 大鼠 WB, FACS, IP, IHC (p), IF (cc), IF (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) antibodyCAPN1 适用: 人 WB, ICC, IP, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) (Middle Region) antibodyCAPN1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) antibodyCAPN1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IP, IHC (p), ELISA 宿主: 小鼠 Monoclonal 15C10 unconjugated
anti-Calpain 1 (CAPN1) (AA 515-526) antibodyCAPN1 适用: 人 WB, IHC, IHC (p), ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) (AA 185-234) antibodyCAPN1 适用: 人, Cow, Pig, 山羊, 兔, 绵羊, Bat, 小鸡, 犬, 豚鼠, 马, 猴, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1 (CAPN1) (AA 300-349) antibodyCAPN1 适用: 人, 小鼠, 大鼠, Cow, Pig, 山羊, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
溶解方式
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
-
缓冲液
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
储存条件
- -20 °C
-
-
-
: "Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease." in: Biochemistry, Vol. 27, Issue 21, pp. 8122-8, (1989) (PubMed).
-
: "Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease." in: Biochemistry, Vol. 27, Issue 21, pp. 8122-8, (1989) (PubMed).
-
- CAPN1 (Calpain 1 (CAPN1))
-
别名
- Calpain 1
-
背景
- Calpain-1 catalytic subunit is a protein that in humans is encoded by the CAPN1 gene. Calpain is an intracellular protease that requires calcium for its catalytic activity. Two isozymes, calpain I (mu-calpain) and calpain II (m-calpain), with different calcium requirements, have been identified. Both are heterodimers composed of L (large, catalytic, 80 kD) and S (small, regulatory, 30 kD) subunits. The isozymes share an identical S subunit, with the differences arising from the L subunits, L1 (CAPN1) and L2. By quantitative RT-PCR, Ueyama et al. (1998) found that expression of calpain-1 and calpain-2 mRNA was significantly increased in muscle biopsy samples derived from 5 men with progressive muscular dystrophy (e.g., DMD, 310200) and 2 men and 3 women with amyotrophic lateral sclerosis (ALS, 105400) compared with controls. Using cDNA clones as probes, Ohno et al. (1989, 1990) assign CANPL1 to chromosome 11.
抗原
-
