CACNA1B 抗体 (C-Term)
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北京 101111
Quick Overview for CACNA1B 抗体 (C-Term) (ABIN965734)
抗原
See all CACNA1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse CACNA1b (Voltage-dependent N-type calcium channel alpha-1B subunit)
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anti-Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) (AA 2132-2339) antibody
CACNA1B 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) antibodyCACNA1B 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) (C-Term) antibodyCACNA1B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B) (AA 851-867), (Intracellular) antibodyKO Validated CACNA1B 适用: 大鼠 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CACNA1B (Calcium Channel, Voltage-Dependent, N Type, alpha 1B Subunit (CACNA1B))
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别名
- CACNA1b
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背景
- Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the `high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Multisubunit complex consisting of alpha-1, alpha2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.
抗原
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