Aurora A 抗体
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- 抗原 See all Aurora A (AURKA) 抗体
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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适用
- 人, 大鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Aurora A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human AURKA expressed in E. Coli.
- 克隆位点
- 1F8
- 亚型
- IgG1
- Top Product
- Discover our top product AURKA Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).
: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).
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Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).
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- 抗原
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
- 别名
- AURKA (AURKA 产品)
- 背景
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Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
Synonyms: AIK, ARK1, AURA, BTAK, STK6, - 分子量
- 48kDa
- 基因ID
- 6790
- 途径
- Cell Division Cycle, Asymmetric Protein Localization
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