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Aurora A 抗体

AURKA 适用: 人, 大鼠, 猴 WB, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 1F8 unconjugated
产品编号 ABIN965625
发货至: 中国
  • 抗原 See all Aurora A (AURKA) 抗体
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    适用
    • 113
    • 66
    • 38
    • 21
    • 18
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 大鼠, 猴
    宿主
    • 106
    • 19
    • 1
    小鼠
    克隆类型
    • 100
    • 25
    单克隆
    标记
    • 77
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aurora A antibody is un-conjugated
    应用范围
    • 92
    • 49
    • 32
    • 23
    • 16
    • 11
    • 10
    • 7
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human AURKA expressed in E. Coli.
    克隆位点
    1F8
    亚型
    IgG1
    Top Product
    Discover our top product AURKA Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • De Luca, Brunetto, Asteriti, Giubettini, Lavia, Guarguaglini: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).

    Veerakumarasivam, Goldstein, Saeb-Parsy, Scott, Warren, Thorne, Mills, Venkitaraman, Neal, Kelly: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).

  • 抗原
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    别名
    AURKA (AURKA 产品)
    背景
    Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
    Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
    Synonyms: AIK, ARK1, AURA, BTAK, STK6,
    分子量
    48kDa
    基因ID
    6790
    途径
    Cell Division Cycle, Asymmetric Protein Localization
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