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Ataxin 10 抗体 (C-Term)

This anti-Ataxin 10 antibody is a 兔 多克隆 antibody detecting Ataxin 10 in IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN965623
发货至: 中国

Quick Overview for Ataxin 10 抗体 (C-Term) (ABIN965623)

抗原

See all Ataxin 10 (ATXN10) 抗体
Ataxin 10 (ATXN10)

适用

  • 26
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  • 3
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  • 2
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  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 36
  • 4

克隆类型

  • 39
  • 2
多克隆

标记

  • 26
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Ataxin 10 antibody is un-conjugated

应用范围

  • 38
  • 15
  • 13
  • 13
  • 9
  • 9
  • 9
  • 6
  • 4
  • 3
  • 1
  • 1
Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ATXN10(Ataxin-10)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Matsuura, Fang, Pearson, Jayakar, Ashizawa, Roa, Nelson: "Interruptions in the expanded ATTCT repeat of spinocerebellar ataxia type 10: repeat purity as a disease modifier?" in: American journal of human genetics, Vol. 78, Issue 1, pp. 125-9, (2005) (PubMed).

    Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).

    Matsuura, Yamagata, Burgess, Rasmussen, Grewal, Watase, Khajavi, McCall, Davis, Zu, Achari, Pulst, Alonso, Noebels, Nelson, Zoghbi, Ashizawa: "Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10." in: Nature genetics, Vol. 26, Issue 2, pp. 191-4, (2000) (PubMed).

  • 抗原

    Ataxin 10 (ATXN10)

    别名

    ATXN10

    背景

    The autosomal dominant cerebellar ataxias (ADCAs) are a clinically and genetically heterogeneous group of disorders characterized by ataxia, dysarthria, dysmetria, and intention tremor. All ADCAs involve some degree of cerebellar dysfunction and a varying degree of signs from other components of the nervous system. Defects in ATXN10 are the cause of spinocerebellar ataxia type 10. SCA10 is an autosomal dominant disorder and is predominantly characterized by cerebellar ataxia seizures. In addition patients often show soft pyramidal signs, ocular dyskinesia, cognitive impairment, and/or behavioral disturbances. SCA10 has been recognized only in families of Mexican origin. The molecular basis of the disease is due to an ATTCT nucleotide repeat expansion in intron 9.
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