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ARL1 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-ARL1 antibody specifically detects ARL1 in IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN965592
发货至: 中国
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Quick Overview for ARL1 抗体 (N-Term) (ABIN965592)

抗原

See all ARL1 抗体
ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ARL1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).

    Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).

  • 抗原

    ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

    别名

    ARL1

    背景

    ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.
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