ARL1 抗体 (N-Term)
Quick Overview for ARL1 抗体 (N-Term) (ABIN965592)
抗原
See all ARL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).
: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).
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ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).
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- ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))
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别名
- ARL1
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背景
- ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.
抗原
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