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APOA5 抗体 (N-Term)

The 兔 多克隆 anti-APOA5 antibody is suitable to detect APOA5 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC.
产品编号 ABIN965570
发货至: 中国
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Quick Overview for APOA5 抗体 (N-Term) (ABIN965570)

抗原

See all APOA5 抗体
APOA5 (Apolipoprotein A-V (APOA5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This APOA5 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human APOA5 (Apolipoprotein A-V precursor)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    APOA5 (Apolipoprotein A-V (APOA5))

    别名

    APOA5

    背景

    APOA5(Apolipoprotein A-V) is a minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. APOA5 may also be associated with chylomicrons. APOA5 is an important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDLTG production rate (without affecting the VLDL-apoB production rate). Three common alleles are known: allele APOA5*1, APOA5*2 and APOA5*3. The APOA5*2 haplotype, which consists of 3 non-coding SNPs, is present in approximately 16% of Caucasians and is associated with increased plasma triglyceride concentrations. APOA5*3 haplotype is defined by the rare Ser-19-Trp substitution. Together, the APOA5*2 and APOA5*3 haplotypes are found in 25 to 50% of African Americans, Hispanics, and Caucasians.

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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