APOA5 抗体
Our Local Distributor
北京 101111
Quick Overview for APOA5 抗体 (ABIN965569)
抗原
See all APOA5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Ni-NTA purified recombinant human Apoa5 expressed in E. Coli strain BL21 (DE3).
-
纯化方法
- Antibodies are purified by protein G affinity chromatography.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Western Blot: Dilution 1: 1,000- 1: 2,000
Suggested ELISA dilution 1: 4,000
ptimized dilution must be determined by end user. -
限制
- 仅限研究用
-
-
-
储存条件
- -20 °C
-
-
- APOA5 (Apolipoprotein A-V (APOA5))
-
别名
- APOA5
-
背景
- Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.
-
基因ID
- 116519
-
途径
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
-