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ALDH1L1 抗体 (C-Term)

Cited in 2+ publications. This 兔 多克隆 anti-ALDH1L1 antibody specifically detects ALDH1L1 in IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN965537
发货至: 中国
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Quick Overview for ALDH1L1 抗体 (C-Term) (ABIN965537)

抗原

See all ALDH1L1 抗体
ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ALDH1L1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse ALDH1L1(Aldehyde dehydrogenase 1 family member L1)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Krupenko, Wagner: "Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35777-84, (2000) (PubMed).

    Case, Kaisaki, Steele: "Resolution of rat liver 10-formyltetrahydrofolate dehydrogenase/hydrolase activities." in: The Journal of biological chemistry, Vol. 263, Issue 21, pp. 10204-7, (1988) (PubMed).

  • 抗原

    ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

    别名

    ALDH1L1

    背景

    ALDH1L1 ((Aldehyde dehydrogenase 1 family member L1) converts 10-formyltetrahydrofolate, a precursor for nucleotide biosynthesis, to tetrahydrofolate. The protein comprises two functional domains: a hydrolase domain that removes a formyl group from 10-formyltetrahydrofolate and a NADP(+)-dependent dehydrogenase domain that reduces the formyl to carbon dioxide. It is localized in cytoplasm and contains 1 acyl carrier domain. In the N-terminal section, it belongs to the GART family. In the C-terminal section, it belongs to the aldehyde dehydrogenase family.
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