CCL4 抗体
Quick Overview for CCL4 抗体 (ABIN964800)
抗原
See all CCL4 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 214-401-b85
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Supplier
- Rockland
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原理
- MIP-1 beta Antibody
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交叉反应 （详细）
- This antibody is specific for swine CCL4 protein.
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产品特性
- Synonyms: rabbit anti-MIP 1 beta Antibody, rabbit anti-MIP-1b Antibody, rabbit anti-CCL4 antibody, CCL4, C-C motif chemokine 4, Small-inducible cytokine A4, Macrophage inflammatory protein 1-beta, MIP-1-beta, ACT-2, MIP-1ß
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纯化方法
- This product was Protein-A purified from monospecific antiserum by chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant protein raised in yeast, corresponding to the 69 amino acids of the mature swine CCL4/MIP1ß protein.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) antibody
CCL4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) antibodyCCL4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7C9E4 unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) antibodyCCL4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8F1C2 unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 26-92) antibodyCCL4 适用: 人, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (Internal Region) antibodyCCL4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) antibodyCCL4 适用: 人 WB, ELISA, IHC (p), Func 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (C-Term) antibodyCCL4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) antibodyCCL4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 22-48) antibodyCCL4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) antibodyCCL4 适用: 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This protein-A purified MIP-1ß antibody has been tested by western blot and is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7.8 kDa in size corresponding to swine CCL4 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500
ELISA Dilution: >1:5,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C upon receipt. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
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别名
- CCL4
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背景
- Background: In many species, both C-C chemokines macrophage inflammatory protein, or MIP-1 alpha (CCL3L1), and MIP-1 beta (CCL4) are structurally and functionally related CC chemokines. They are both potent chemoattractants for monocytes, which form an important component of the stroma of tumor tissue, and in humans may regulate tumor growth and associated inflammation. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. Both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes, but their effect on lymphocytes differ. MIP-1 alpha selectively attracts CD8+ lymphocytes, while MIP-1 beta selectively attracts CD4+ lymphocytes. They contain the four highly conserved cysteine residues present in CC chemokines. MIP-1 beta (CCL4) has specificity for CCR5 receptors. In humans, it is also a major HIV-suppressive factor produced by CD8+ T cells.
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基因ID
- 396668
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UniProt
- Q711P4
抗原
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