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IL-2 抗体

IL2 适用: Cat WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN964739
Supplier Product No.: 202-401-b95
发货至: 中国
  • 抗原 See all IL-2 (IL2) 抗体
    IL-2 (IL2) (Interleukin 2 (IL2))
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    标记
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    This IL-2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    Supplier Product No.
    202-401-b95
    Supplier
    Rockland
    原理
    IL-2 Antibody
    交叉反应 (详细)
    This antibody is specific for cat IL-2 protein.
    产品特性
    Synonyms: rabbit anti-Interleukin-2, rabbit anti-IL-2 antibody, IL2, T-cell growth factor, TCGF, Aldesleukin, Lymphokine
    纯化方法
    This product was protein A purified from monospecific antiserum by chromatography.
    免疫原

    Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 134 amino acids of mature cat IL-2.

    Immunogen Type: Recombinant Protein

    亚型
    IgG
    Top Product
    Discover our top product IL2 Primary Antibody
  • 应用备注

    Application Note: This protein A purified IL-2 antibody has been tested by ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 15.4 kDa in size corresponding to feline IL-2 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500-1:2,000

    ELISA Dilution: 1:20,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    IL2 (IL2 产品)
    背景
    Background: IL-2 is a member of a family of cytokines, which also includes IL-4, IL-7, IL-9, IL-15 and IL-21. All members of this family signal through a receptor complex that includes the common gamma chain. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 receptor beta (CD122) and the common gamma chain. The main function of IL-2 is to promote the development of T regulatory cells. IL-2 is produced by several cell types including, B cells, gamma-delta T cells, CD4+ T cells, CD8+ T cells, and eosinophils. It has been found to be similar to IL-15 in terms of function. Both IL-2 and IL-15 are able to facilitate production of immunoglobulins made by B cells and induce the differentiation and proliferation of natural killer cells. The primary differences between IL-2 and IL-15 are found in adaptive immune responses: IL-2 participates in maintenance of T-Regs and reduces self-reactive T cells while IL-15 is necessary for maintaining highly specific T cell responses by supporting survival of CD8 memory T cells.
    基因ID
    751114
    NCBI登录号
    NP_001036802
    UniProt
    Q07885
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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