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Outer Surface Protein C (B. Burgdorferi) (OspC) 抗体

Cited in 4+ publications. This 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA 和 WB. The antibody is reactive with Borrelia burgdorferi samples.
Rockland
产品编号 ABIN964717
Supplier Product No.: 200-401-c11
发货至: 中国
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Quick Overview for Outer Surface Protein C (B. Burgdorferi) (OspC) 抗体 (ABIN964717)

抗原

Outer Surface Protein C (B. Burgdorferi) (OspC)

适用

Borrelia burgdorferi

宿主

  • 1

克隆类型

  • 1
多克隆

标记

  • 1
非结合性

应用范围

ELISA, Western Blotting (WB)
  • Supplier Product No.

    200-401-c11

    Supplier

    Rockland

    原理

    OspC Antibody

    交叉反应 (详细)

    This antibody is specific for Borrelia burgdorferi OspC protein.

    产品特性

    Synonyms: rabbit anti-OspC Antibody, Borrelia burgdorferi OspC, PC, Outer Surface Protein C, BB_B19

    纯化方法

    This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography.

    免疫原

    Immunogen: MBP-fusion protein corresponding to Borrelia burgdorferi OspC protein.

    Immunogen Type: Recombinant Protein

    亚型

    IgG
  • 应用备注

    Application Note: This protein-A purified antibody has been tested for use in Western blotting and in ELISA. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 20.7 kDa in size corresponding to Borrelia burgdorferi OspC protein by Western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:1,000

    Other: User Optimized

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    浓度

    1.0 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • Karvonen, Tammisto, Nykky, Gilbert: "Borrelia burgdorferi Outer Membrane Vesicles Contain Antigenic Proteins, but Do Not Induce Cell Death in Human Cells." in: Microorganisms, Vol. 10, Issue 2, (2022) (PubMed).

    Joung, Ballard, Ma, Tseng, Teshome, Burakowski, Garner, Di Carlo, Ozcan: "Paper-based multiplexed vertical flow assay for point-of-care testing." in: Lab on a chip, Vol. 19, Issue 6, pp. 1027-1034, (2019) (PubMed).

    Caine, Lin, Kessler, Sato, Leong, Coburn: "Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival." in: Cellular microbiology, Vol. 19, Issue 12, (2018) (PubMed).

    Caine, Coburn: "A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream survival conferred by adhesion proteins." in: Infection and immunity, Vol. 83, Issue 8, pp. 3184-94, (2015) (PubMed).

  • 抗原

    Outer Surface Protein C (B. Burgdorferi) (OspC)

    别名

    ospC

    物质类

    Bacteria Protein

    背景

    Background: Outer Surface Protein C, or OspC, is a 20.7 kDa immunogenic protein on the outer surface of the spirochete Borrelia burgdorferi. Its function is not known, but it is located with lipid-anchoring sites on the outer cell membrane.

    基因ID

    1194415

    NCBI登录号

    WP_010890595

    UniProt

    Q07337
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