ODF2 抗体
Quick Overview for ODF2 抗体 (ABIN964607)
抗原
See all ODF2 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-c43
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Supplier
- Rockland
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原理
- Cenexin-1 Antibody
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交叉反应 （详细）
- It is directed against, and shows specific reactivity for, human Cenexin-1 protein.
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产品特性
- Synonyms: rabbit anti-Cenexin-1 Antibody, ODF84 antibody, Outer dense fiber of sperm tail 2 antibody, Cenexin1 variant 1 antibody, KKT 4 antibody, Cenexin 1
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纯化方法
- This antibody was purified from monospecific antiserum by protein-A purified immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a truncated recombinant protein hCenexin1.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) antibody
ODF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 706-804) antibodyODF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 630-829) antibodyODF2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (Internal Region) antibodyVerified ODF2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 218-267) antibodyODF2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔, Pig, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (N-Term) antibodyODF2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) antibodyODF2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (N-Term) antibodyODF2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (C-Term) antibodyODF2 适用: 人, Chimpanzee, Macaque WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (pSer796) antibodyODF2 适用: 人, Chimpanzee, Macaque WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: Anti-Cenexin-1 purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 93 kDa in size corresponding to Cenexin-1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500-1:2000
ELISA Dilution: 1:500 - 1:10,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.53 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))
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别名
- ODF2
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背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenexin-1 (ODF84) and cenexin-2 are splicing variants that are expressed from the same genetic locus Outer Dense Fiber protein 2 (ODF2) . Cenexin-1 and cenexin-2, regarded as centriolar proteins. Cenexin-1, a 93-kD variant of ODF2, is the major form of cennexin expressed in various somatic cells and tissues and associates with centrosomes. Cenexin-1 contains a unique C-terminal extension that appears to play a critical role in recruiting mitotic regulators such as polo-like kinase 1. In contrast, ODF2, a 70- kDa protein, is a major component of sperm tail cytoskeleton and abundantly expressed in testis. Additional evidence suggests that both of these proteins play important role in primary cilia formation. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. Cenexin-1 is one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of the cenexin gene, however, not all isoforms and variants have been fully described.
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基因ID
- 4957
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NCBI登录号
- NP_702915
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UniProt
- Q5BJF6
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途径
- M Phase
抗原
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