CCL3L1 抗体
Quick Overview for CCL3L1 抗体 (ABIN964604)
抗原
See all CCL3L1 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-b61
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Supplier
- Rockland
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原理
- CCL3L1 Antibody
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交叉反应 （详细）
- This antibody is specific for swine CCL3L1 protein.
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产品特性
- Synonyms: rabbit anti-CCL3L1 Antibody, CCL3L3, Chemokine (C-C motif) ligand 3-like 1, macrophage inflammatory protein 1 alpha, MIP-1 alpha, ld78beta, scya3l1, small inducible cytokine a3-like 1
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纯化方法
- This product was Protein-A purified from monospecific antiserum by chromatography.
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免疫原
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 70 amino acids of the mature swine CCL3L1 protein.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1) (AA 1-93) antibody
CCL3L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1) antibodyCCL3L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1) (AA 24-93) antibodyCCL3L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This protein-A purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7.8 kDa in size corresponding to swine CCL3L1 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: User Optimized
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))
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别名
- CCL3L1
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背景
- Background: Chemokine (C-C motif) ligand 3-like 1 (CCL3L1), also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha, other synonyms: ld78beta, scya3l1, small inducible cytokine a3-like 1), is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. In humans, CCL3L1 is encoded by a variable copy-number gene. The CC family induces MCP1 and RANTES, and exhibits a variety of proinflammatory activities including chemotaxis, and functional and proliferative activation of leukocytes, lymphocytes, and macrophages. Its signal is transmitted through transmembrane receptors, CC chemokine receptors, CCR1, CCR3 and CCR5. CCL3L1/MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils. CCL3L1 binds to several chemokine receptors. In humans these receptors include chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. In swine, CCL3L1 protein is 86 % similar to CCL4 protein, and 73 % similar to CCL5.
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基因ID
- 494459, 57527998
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UniProt
- A1YM34
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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