ITGB1 抗体
Quick Overview for ITGB1 抗体 (ABIN960569)
抗原
See all ITGB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody (subclass IgG1) binds to human b1-integrin chain present on tumor cells. BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.
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纯化方法
- Purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG1
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应用备注
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Approved: Flo, Func, IP, WB
Usage: For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of beta1 integrin to be inactivated. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- 4°C. Store undiluted.
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- ITGB1 (Integrin beta 1 (ITGB1))
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别名
- ITGB1 / Integrin Beta 1 / CD29
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背景
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Name/Gene ID: ITGB1
Family: Integrin
Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta -
基因ID
- 3688
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UniProt
- P05556
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途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
抗原
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