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CDNF 抗体

Cited in 1 publication. This anti-CDNF antibody is a 小鼠 单克隆 antibody detecting CDNF in WB 和 ELISA. Suitable for 人.
产品编号 ABIN956415
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDNF 抗体 (ABIN956415)

抗原

See all CDNF 抗体
CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDNF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

7D6
  • 特异性

    Human, CDNF protein

    纯化方法

    purified by protein G affinity chromatography

    免疫原

    Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant

    亚型

    IgG1
  • 应用备注

    ELISA: 1:64 000, WB: 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format

    说明

    Synonym: ARMETL1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/ml

    缓冲液

    PBS pH 7.4, with 0.1%

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.

    储存条件

    -20 °C

    储存方法

    This product is shipped in non-frozen liquid form in ambient conditions
  • Galli, Lindholm, Kontturi, Saarma, Urtti, Yliperttula: "Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy." in: Cell transplantation, Vol. 28, Issue 4, pp. 413-424, (2020) (PubMed).

  • 抗原

    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

    别名

    CDNF

    背景

    CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta

    UniProt

    Q49AH0
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