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ZP4 抗体 (C-Term)

This anti-ZP4 antibody is a 兔 多克隆 antibody detecting ZP4 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN955755
发货至: 中国

Quick Overview for ZP4 抗体 (C-Term) (ABIN955755)

抗原

See all ZP4 抗体
ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

适用

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宿主

  • 28

克隆类型

  • 28
多克隆

标记

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This ZP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 452-482, C-Term

    特异性

    This antibody detects ZP4 / ZPB (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human ZP4

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

    别名

    ZP4 / ZPB

    背景

    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.Synonyms: Zona pellucida protein B, Zona pellucida sperm-binding protein 4

    基因ID

    57829

    NCBI登录号

    NP_067009
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