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WT1 抗体 (Middle Region)

This anti-WT1 antibody is a 兔 多克隆 antibody detecting WT1 in IF, WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN955586
发货至: 中国

Quick Overview for WT1 抗体 (Middle Region) (ABIN955586)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 353-383, Middle Region

    特异性

    This antibody detects Wilms tumor protein (Center).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 353-383 (E361) amino acids from the Central region of human WT1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    WT1 / Wilms Tumor Protein

    背景

    This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].Synonyms: WT33

    基因ID

    7490

    NCBI登录号

    NP_000369

    途径

    Tube Formation
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