WT1 抗体 (Middle Region)
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Quick Overview for WT1 抗体 (Middle Region) (ABIN955586)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 353-383, Middle Region
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特异性
- This antibody detects Wilms tumor protein (Center).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 353-383 (E361) amino acids from the Central region of human WT1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1 / Wilms Tumor Protein
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背景
- This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].Synonyms: WT33
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基因ID
- 7490
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NCBI登录号
- NP_000369
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途径
- Tube Formation
抗原
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