WDR48 抗体 (C-Term)
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Quick Overview for WDR48 抗体 (C-Term) (ABIN955556)
抗原
See all WDR48 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 610-638, C-Term
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特异性
- This antibody detects WDR48 / p80 (C-term).
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 610-638 amino acids from the C-terminal region of human WDR48
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亚型
- Ig Fraction
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anti-WD Repeat Domain 48 (WDR48) (AA 450-677) antibody
WDR48 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) antibodyWDR48 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630), (C-Term) antibodyWDR48 适用: 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28145 unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630), (C-Term) antibodyWDR48 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630) antibodyWDR48 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) antibodyWDR48 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- WDR48 (WD Repeat Domain 48 (WDR48))
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别名
- WDR48 / p80
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背景
- Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 by enhancing the USP1-mediated deubiquitination of FANCD2, USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12 and USP46, respectively. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. In case of infection by Herpesvirus saimiri, may play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. Induces lysosomal vesicle formation via interaction with Herpesvirus saimiri tyrosine kinase-interacting protein (TIP). Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptor TCR. May play a role in generation of enlarged endosomal vesicles via interaction with TIP. In case of infection by papillomavirus HPV11, promotes the maintenance of the viral genome via its interaction with HPV11 helicase E1.Synonyms: KIAA1449, UAF1, USP1-associated factor 1, WD repeat endosomal protein, WD repeat-containing protein 48
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基因ID
- 57599
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NCBI登录号
- NP_065890
抗原
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