Uromodulin 抗体
Quick Overview for Uromodulin 抗体 (ABIN955477)
抗原
See all Uromodulin (UMOD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Anti-Human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. This monoclonal antibody has shown good localization to the distal tubule and collecting duct as well as to large deposits of Tamm-Horsfall protein which has clogged peri-pelvic veins.
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交叉反应 （详细）
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Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Protein G Chromatography.
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免疫原
- Human Tamm-Horsfall protein.
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亚型
- IgG2b
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anti-Uromodulin (UMOD) (AA 351-450) antibody
UMOD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 25-120) antibodyUMOD 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Uromodulin (UMOD) (AA 32-151) antibodyUMOD 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 334-589) antibodyUMOD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) antibodyUMOD 适用: 人, 犬 IHC, IHC (p), IF, IHC (fro) 宿主: 小鼠 Monoclonal 10-32 unconjugated
anti-Uromodulin (UMOD) (C-Term) antibodyUMOD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 335-590) antibodyUMOD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 30-150) antibodyUMOD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Uromodulin (UMOD)
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背景
- Tamm-Horsfall Protein (THP) is a glycoprotein of approximately 80 kDa containing up to 25 % carbohydrate by weight. It exists as a high molecular weight polymer in urine and approximately 50 mg of the THP are excreted per day by adult humans. THP is produced by the epithelial cells lining the thick ascending loop of Henle and distal convoluted tubules of the kidney. THP is also the primary constituent of renal tubular casts and THP aggregation has been implicated as a factor in the pathogenesis of acute renal failure by causing tubular obstruction. Antibody to THP is present in the serum of patients with pyelonephritis and reflus uropathy.Synonyms: THP, Tamm-Horsfall urinary glycoprotein
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基因ID
- 7369
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NCBI登录号
- NP_001008390
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UniProt
- P07911
抗原
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