TRAF4 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TRAF4 抗体 (C-Term) (ABIN955308)
抗原
See all TRAF4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 426-455, C-Term
-
特异性
- This antibody detects TRAF4 / RNF83 (C-term).
-
交叉反应 (详细)
- Species reactivity (tested):Human
-
纯化方法
- Protein A column followed by peptide affinity purification
-
免疫原
- KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human TRAF4
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
-
-
- TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
-
别名
- TRAF4 / RNF83
-
背景
- This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.Synonyms: CART1, Cysteine-rich domain associated with RING and Traf domains protein 1, MLN62, Malignant 62, RING finger protein 83, TNF receptor-associated factor 4
-
基因ID
- 9618
-
NCBI登录号
- NP_004286
抗原
-