TNIP1 抗体 (C-Term)
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Quick Overview for TNIP1 抗体 (C-Term) (ABIN955281)
抗原
See all TNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 454-482, C-Term
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特异性
- This antibody detects TNIP1 (C-term).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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别名
- TNIP1
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背景
- Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.Synonyms: HIV-1 Nef-interacting protein, KIAA0113, NAF1, Nef-associated factor 1, Nip40-1, TNFAIP3-interacting protein 1, VAN, Virion-associated nuclear shuttling protein
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基因ID
- 10318
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NCBI登录号
- NP_006049
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途径
- Activation of Innate immune Response
抗原
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