TMPRSS12 抗体 (N-Term)
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Quick Overview for TMPRSS12 抗体 (N-Term) (ABIN955267)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-54, N-Term
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特异性
- This antibody detects TMPRSS12 (N-term).
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human TMPRSS12
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亚型
- Ig Fraction
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anti-Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12) (AA 215-264) antibody
TMPRSS12 适用: 人, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12) (AA 26-54), (N-Term) antibodyTMPRSS12 适用: 人 WB 宿主: 兔 Polyclonal RB35931 unconjugated
anti-Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12) (Middle Region) antibodyTMPRSS12 适用: 人, 豚鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))
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别名
- TMPRSS12
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背景
- TMPRSS12 (transmembrane protease serine 12) is a 348 amino acid single-pass membrane protein that belong to the peptidase S1 family and contains one peptidase S1 domain. The gene that encodes TMPRSS12 consists of nearly 45,000 bases and maps to human chromosome 12q13.12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism.Synonyms: Transmembrane protease serine 12
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基因ID
- 283471
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NCBI登录号
- NP_872365
抗原
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