TIMP1 抗体 (C-Term)
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Quick Overview for TIMP1 抗体 (C-Term) (ABIN955221)
抗原
See all TIMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-195, C-Term
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特异性
- This antibody detects TIMP1 (C-term).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 164-195 amino acids from the C-terminal region of human TIMP1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1
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背景
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.Synonyms: CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases
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基因ID
- 7076
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NCBI登录号
- NP_003245
抗原
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